Can only catch the first Pokémon encountered in each area, and none else. If the first Pokémon encountered faints or flees, there are no second chances. (Dupes Clause and Shiny Clause)Any Pokémon that faints is considered dead, and must be released at soonest possible chance.
Must nickname all of the caught Pokémon.
No reloading the game when things go wrong. (Duh)Black/White-ing out is considered Game Over.Can use an HM Slave if none of the battle Pokémon can learn the needed move. This Pokémon is not allowed to battle.Can catch Kyurem. Heavy limits on what battles it can be used in.